THIS drops as you age. How to fix it. (NEW STUDY)

High Blood Pressure: The Silent Killer [00:00]

• High blood pressure is often called the "silent killer" because it typically has no symptoms and goes unnoticed.
• It affects over 1 billion people worldwide and dramatically increases the risk of heart attack and stroke.
• Almost 50% of adults in the United States have elevated blood pressure, many without knowing it.
• While often asymptomatic, high blood pressure silently damages arteries, the heart, and long-term health span.

"And that is high blood pressure. We're also going to talk about an exciting new human study that may point to a simple way to support the body's own natural system for keeping blood vessels healthy."

The Role of Nitric Oxide (NO) in Aging [01:09]

• A key driver of increased cardiovascular risk with age is the decline of nitric oxide (NO).
• NO is a signaling molecule that relaxes and widens blood vessels, supports artery wall function, improves blood flow, and aids mitochondrial efficiency.
• As we age, NO production drops, leading to stiffer blood vessels, rising blood pressure, and decreased exercise capacity.
• Boosting nitric oxide is a significant focus for those interested in longevity and maintaining health throughout life.

Nitrolis: A Novel Supplement for Nitric Oxide Support [01:53]

• Do Not Age.org, a health research organization, has developed a proprietary supplement called Nitrolis.
• Nitrolis is designed to support nitric oxide bioavailability through multiple pathways.
• Its formulation includes fermented beet (rich in dietary nitrate), magnesium sorbate, and epimedium (horny goat weed).
• The supplement aims to support nitric oxide production naturally and consistently, benefiting everyday cardiovascular health, not just for athletes.

Groundbreaking Human Study on Nitrolis [02:32]

• A randomized, placebo-controlled human trial, considered the gold standard, was conducted to evaluate Nitrolis.
• The 30-day study involved 85 adults aged 30-70, divided into Nitrolis and placebo groups.
• Participants in the Nitrolis group took 400 mg daily.
• Nitric oxide levels were measured using salivary strips on days 1, 15, and 30.

"The study lasted for 30 days. 85 adults participated, ages 30 through 70. They're split into two different groups, the Nitrolis group and the placebo group."

Astonishing Results: Nitric Oxide Boost [03:03]

• By day 30, the Nitrolis group showed dramatic improvements in nitric oxide levels.
• The median increase was +90 units, and the mean increase was +108 units.
• The average percentage increase in NO was an astounding 226% above baseline.
• The placebo group showed almost no change in nitric oxide levels.
• These results were robust, not driven by a few outliers, and demonstrated a meaningful change relative to baseline.

Responder Rate: Quantifying Significant Improvement [03:47]

• A "responder" was defined as someone who increased NO levels by 70 units or more.
• In the Nitrolis group, 60.5% of participants were responders.
• In contrast, only 11.9% of participants in the placebo group were responders.
• This means the Nitrolis group had over five times the responder rate compared to the placebo group.
• Participants noticed improvements as early as day one, with responder rates helping to confirm the consistency of the results.

"The Nitrolis group was 60.5% and the placebo group was 11.9%. That's over five times higher."

Real-World Implications for Health [04:46]

• Elevated nitric oxide levels are linked to better blood pressure control, healthier arteries, improved circulation, and enhanced exercise performance.
• Supporting NO may help address a root mechanism of cardiovascular aging, especially for older adults more vulnerable to rising blood pressure.
• This could contribute to better overall cardiovascular health and healthy aging.

Study Caveats and Future Directions [05:14]

• This was a pilot study with a relatively short duration of 30 days.
• Salivary strips are semi-quantitative, providing an estimate rather than an exact numerical measurement.
• The researchers were affiliated with Do Not Age, a fact stated in the study's conflicts of interest section.
• While these findings are promising, more studies are needed to fully understand long-term benefits and potential side effects.

"These results were exciting and very promising, but more studies will help us fully understand the benefits and potential side effects with long-term use."

The Takeaway: Prioritizing Nitric Oxide [06:14]

• The study suggests Nitrolis can significantly improve nitric oxide levels, supporting healthier blood pressure and vascular function.
• For individuals over 40, paying attention to nitric oxide levels is crucial for heart protection and maintaining healthy blood flow.
• Supporting NO through diet, sunlight, exercise, and supplements like Nitrolis may be a vital long-term strategy for cardiovascular health and healthy aging.